Research projects

Joanna Groom Headshot

Active Australia

Melanoma

Could melanoma be treated with a vaccine?

Melanoma is an aggressive type of skin cancer which can be hard to treat so this project is looking to kick-start a game-changing vaccine which could be a new type of cure. 

Researcher: Dr Joanna Groom

Precision vaccines and the potential for better immunotherapies
Diana Blaydon and Team saying thanks

Active United Kingdom

Oesophageal cancer

How does the genetic disease tylosis cause oesophageal cancer?

Researchers hope to reveal ways to diagnose oesophageal cancer sooner and help treatments work better by better understanding the earliest stages of the disease.

Researcher: Dr Diana Blaydon

Revealing the earliest signs of oesophageal cancer
Katrin Ottersbach in the lab

Active United Kingdom

Leukaemia

How does infant leukaemia develop and how can we stop it?

Infant leukaemia is very difficult to treat so researchers are hoping to better understand its unique biology to reveal vital better and kinder treatments.

Researcher: Professor Katrin Ottersbach

Identifying new treatments for infant leukaemia
Jamie Rossjohn Headshot

Active Australia

Leukaemia

Can we help immunotherapies treat leukaemia better?

This project hopes to reveal new, better, immunotherapy treatments for leukaemia by boosting a different cell in our immune system from other treatments. 

Researcher: Professor Jamie Rossjohn

Revealing the role of natural killer cells in cancer immunity
Inbal Wortzel Headshot

Active USA

Multiple cancers

What makes it easier for some cancers to spread to other organs?

Exploring how ‘messages’ sent from cancer cells to other parts of the body might help cancers to spread and whether new cures could stop this process.

Researcher: Dr Inbal Wortzel

A new way to predict and treat the spread of cancer
Lee Wong and Team

Active Australia

Brain cancer

Can new targeted treatments help treat aggressive brain cancers?

Researchers hope to improve outcomes for brain cancer patients by explore whether tumours with particular mutations can be treated using a targeted therapy 

Researcher: Dr Lee Wong

Tackling tough-to-treat brain cancers with new targeted treatments
Robert Falconer Headshot

Active United Kingdom

Neuroblastoma

Can we target neuroblastoma cells without harming healthy cells?

Lots of cancer drugs cause nasty side effects by affecting healthy cells, so this project is looking for ways to turn on drugs only when they are in the tumour. 

Researcher: Professor Robert Falconer

Target acquired: Making ‘prodrugs’ for neuroblastoma that leave healthy cells unharmed
Peter Carmeliet Team Shot

Active Belgium

Lung cancer

Can we re-wire our cells to help our immune system attack cancer?

Immunotherapy doesn’t always work but researchers hope to find ways to re-wire some of our cells so that these treatments can help more patients in the future.

Researcher: Professor Peter Carmeliet

Rewiring blood cells that block the immune response with AI
Johanna Ivaska Headshot

Active Finland

Breast cancer

Can we stop breast cancer before it spreads to other organs?

Stopping breast cancer spreading would make it much easier to treat so this project is exploring a molecule that appears to stop tumours spreading.

Researcher: Professor Johanna Ivaska

Harnessing the power of healthy breast cells to keep cancer at bay

We only fund the best ideas…

Our world-class Scientific Advisory Committee chooses which research projects we fund, using strict criteria

Our Scientific Advisory Committee

Our Board of Trustees oversees the charity, ensuring we meet our aims in both fundraising and awarding research grants

Our Board of Trustees

Through co-funding and working together, we can advance research quickly and support more innovative ideas

Co-funding opportunities
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